PPIF and SLC25A4

Number of citations of the paper that reports this interaction (PubMedID 9874241)
120

Data Source:
HPRD (in vitro)

		PPIF	SLC25A4
Description		peptidylprolyl isomerase F	solute carrier family 25 member 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Integral Component Of Plasma Membrane Membrane Integral Component Of Mitochondrial Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Oxidative Phosphorylation Uncoupler Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Response To Ischemia Protein Folding Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of Necrotic Cell Death Negative Regulation Of ATPase Activity Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial Genome Maintenance Generation Of Precursor Metabolites And Energy Apoptotic Mitochondrial Changes Adenine Transport ADP Transport Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Necroptotic Process Mitochondrial ADP Transmembrane Transport Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Adaptive Thermogenesis
Pathways			Mitochondrial protein import Mitochondrial protein import Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs		Cyclosporine Proline Triglyme Coumarin 120	ATP Clodronic acid Etidronic acid [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Tetrastearoyl cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Triglyceride levels ( 32203549)
Interacting Genes		19 interacting genes: ABI2 AGTRAP ARFIP2 BANP CIDEB CMTM5 FAM25A FAM25C FAM25G FKBP7 MAGEA11 MUC1 PRB3 SERPINB5 SLC25A4 SYP SYPL1 VDAC1 YIF1A	7 interacting genes: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE
Entrez ID		10105	291
HPRD ID		06839	00058
Ensembl ID		ENSG00000108179	ENSG00000151729
Uniprot IDs		A0A024QZS4 P30405	A0A0S2Z3H3 P12235
PDB IDs		2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1 6Y3E 6YBM
Enriched GO Terms of Interacting Partners?
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