MAP1LC3C and TP53INP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MAP1LC3C	TP53INP1
Description		microtubule associated protein 1 light chain 3 gamma	tumor protein p53 inducible nuclear protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Protein Binding Antioxidant Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Autophagosome Assembly Apoptotic Process Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Autophagy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Negative Regulation Of Myofibroblast Differentiation
Pathways		Macroautophagy	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)	Alzheimer's disease ( 31473137) Fasting glucose ( 34059833) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Macular thickness ( 30535121) Platelet distribution width ( 32888494) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 22885922 24509480 30054458 30297969 32499647 20581827 28869590) Urate levels ( 31578528)
Interacting Genes		32 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATXN3 CALCOCO2 CAPN3 CUL3 GMEB2 IRGM KBTBD6 KBTBD7 LAT LMNB1 MEFV MISP NEDD4 OPRM1 OPTN RHOXF1 RUFY4 STK3 TAX1BP1 TBC1D25 TNIP1 TP53INP1 TRIM21 TRIM32 TSR2 WDFY3 WDR81 ZNF24	11 interacting genes: GABARAP GABARAPL1 GABARAPL2 HIPK2 MAP1LC3A MAP1LC3C SEC22A SQSTM1 TP53 UNC119 YPEL3
Entrez ID		440738	94241
HPRD ID		14226	09367
Ensembl ID		ENSG00000197769	ENSG00000164938
Uniprot IDs		Q9BXW4	A0A024R9C8 Q96A56
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW
Enriched GO Terms of Interacting Partners?
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