AFDN and SORBS2

  • Number of citations of the paper that reports this interaction (PubMedID 10521485)
  • 25
  • Data Source:
  • HPRD (in vitro)

AFDN

SORBS2

Description afadin, adherens junction formation factor sorbin and SH3 domain containing 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906)
  • Cardiac Troponin-T levels ( 31014085)
  • Coronary artery disease ( 33020668)
  • Cytokine and corticosteroid-stimulated IL-6 production ( 25896417)
  • Cytokine-stimulated IL-6 production ( 25896417)
  • Height ( 31562340)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Short-term memory (digit-span task) ( 30741946)
  • Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes 39 interacting genes: BCR CCR6 CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NECTIN1 NECTIN2 NECTIN3 NECTIN4 NRXN1 NRXN2 NRXN3 PFN1 PICK1 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RPS6KA2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG 47 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 DYNC1H1 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SHANK3 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ
Entrez ID 4301 8470
HPRD ID 01164 12473
Ensembl ID ENSG00000130396 ENSG00000154556
Uniprot IDs A8MQ02 G1UI22 J3KN01 P55196 B7Z3D7 B7Z997 O94875
PDB IDs 1T2M 1XZ9 2AIN 2EXG 5A6C 5VEI
Enriched GO Terms of Interacting Partners?
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