Description |
mitogen-activated protein kinase kinase kinase 1 |
GRIP1 associated protein 1 |
Image |
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No pdb structure |
GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alanine aminotransferase levels ( 33547301 33339817)
- Alanine transaminase levels ( 29403010)
- Blond vs. brown/black hair color ( 30531825)
- Body shape index ( 34021172)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683 17529967 23535729 31757997 20453838 19330030)
- Breast cancer (early onset) ( 24493630)
- Brown vs. black hair color ( 30531825)
- Coronary artery disease ( 29212778)
- Cortical surface area (MOSTest) ( 32665545)
- Fasting blood insulin ( 25631608)
- Fasting glucose in pregnancy (gestational week 14-16) ( 30324795)
- Fasting insulin ( 33402679)
- Fasting insulin (dietary factor interaction) ( 24204828)
- Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
- Initial pursuit acceleration ( 29064472)
- Lung function (FEV1) ( 30061609)
- Refractive error ( 32231278)
- Serum alkaline phosphatase levels ( 33547301)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Subcortical volume (MOSTest) ( 32665545)
- Triglyceride levels ( 28334899 32902719)
- Triglycerides ( 24097068 20686565)
- Type 2 diabetes ( 23209189)
- Urate levels (BMI interaction) ( 25811787)
- Waist circumference ( 23966867)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-hip index ( 34021172)
- Waist-hip ratio ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
- White matter hyperintensity volume ( 33293549)
- White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
- White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
- Youthful appearance (self-reported) ( 32339537)
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- Eosinophil percentage of white cells ( 32888494)
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Interacting Genes |
97 interacting genes:
ACTN1
APEX2
APPL1
ARHGAP4
ASCC2
ATXN3
BAALC
BAP1
BRCA1
CARD14
CCDC69
CD74
CEP85
CHRM5
CHUK
COPS6
CRELD1
CRTC1
CUEDC1
DCUN1D1
DCUN1D2
DENND6B
DNAJB2
DNAJB6
DTX1
EPHA1
EPN1
FAF2
FAM184A
FKBP6
GGA2
GRIPAP1
GSK3B
HBS1L
HGS
HIP1
IKBKB
ILRUN
IMPACT
KRT36
MAP2K4
MAP2K7
MAPK1
MAPK9
MBP
MINDY3
NEK10
NFKBIA
NOTCH1
NPLOC4
NR4A1
ODF2
PAK1
PLEKHB2
PSMD4
RAB3IL1
RABEP2
RAD18
RAD23A
RAD51AP1
RAF1
RBCK1
RIPK1
RNF114
RNF126
RNF141
SPART
STAM
STAM2
TAB1
TNIP1
TOM1
TOM1L2
TP53
TRAF2
UBAC1
UBAP1
UBASH3B
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2G1
UBE2I
UBE2K
UBE2L6
UBE2V1
UBE2W
UBQLN1
UBXN7
UCHL5
UFD1
USP28
YWHAE
ZFAND3
ZFAND5
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73 interacting genes:
AARD
ANKRD11
ARL15
ATG5
BYSL
CASP3
CBX8
CCDC103
CCDC185
CCDC187
CCNB3
CCNH
CCNT1
CDC37
CEP57L1
CFAP53
CWF19L2
DAXX
DISC1
DUSP26
EHHADH
ELOA
ENKD1
FAM161A
FAM50B
FAM90A1
FXR1
GAS8
GPR173
GRIA1
GRIP1
GRM7
HDAC4
HSPB1
ING4
ING5
LNX1
MAGED4B
MAP3K1
MEOX2
MFAP1
MLLT6
NUAK2
PIBF1
PKP2
PPP1R18
PRPF18
PSMB1
RAB4A
RCOR3
SMAD2
SMARCE1
SMURF1
SNAPC5
SNW1
SPP1
STAP1
TBC1D30
TCEA2
TCP10L
TEPSIN
TES
TRAF2
TSGA10IP
TSHZ2
TSNAX
TTC23
USP2
ZMAT2
ZNF219
ZNF250
ZNF35
ZNF835
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Entrez ID |
4214 |
56850 |
HPRD ID |
19599 |
02325 |
Ensembl ID |
ENSG00000095015
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ENSG00000068400
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Uniprot IDs |
Q13233
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Q4V328
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PDB IDs |
6WHB
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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