MEF2A and MEOX1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		MEF2A	MEOX1
Description		myocyte enhancer factor 2A	mesenchyme homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding Histone Acetyltransferase Binding Histone Deacetylase Binding Sequence-specific DNA Binding SMAD Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitochondrial Genome Maintenance Negative Regulation Of Transcription By RNA Polymerase II MAPK Cascade Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Apoptotic Process Heart Development Muscle Organ Development Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Mitochondrion Distribution Dendrite Morphogenesis Ventricular Cardiac Myofibril Assembly Cardiac Conduction ERK5 Cascade Cellular Response To Calcium Ion	Somite Specification Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development
Pathways		ERK/MAPK targets Myogenesis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Cervical cancer ( 28806749) Dental caries (decayed and filled deciduous teeth) ( 31533690) Gestational age at birth (maternal effect) ( 28598419) Systolic blood pressure ( 30224653 30578418)	Fractures ( 30158200)
Interacting Genes		30 interacting genes: ACTN4 ASCL1 CASP3 CASP7 CDK5 DDB1 DNMT3L EP300 ERBIN HAND1 HDAC4 HDAC5 HDAC7 HDAC9 HSF2BP MAPK14 MAPK7 MEF2D MEOX1 MYOD1 MYOG NDUFB9 PHB2 SCAND2P SMAD2 SMAD4 SUMO1 TEAD1 THRA VGLL4	99 interacting genes: ACBD4 ACOT12 ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf109 C1orf50 C2CD6 CACNB3 CCDC102B CCDC103 CDC34 CIAO1 CIB3 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DUSP3 EIF4A3 EIF4EBP1 EMD FAM126B FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TEX33 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410
Entrez ID		4205	4222
HPRD ID		02807	02537
Ensembl ID		ENSG00000068305	ENSG00000005102
Uniprot IDs		A0A0S2Z417 A0A0S2Z453 A0A0S2Z454 A0A0S2Z4C8 A0A0S2Z4N0 A8K720 Q02078	P50221
PDB IDs		1C7U 1EGW 1LEW 3KOV 3MU6 3P57 6BYY 6BZ1
Enriched GO Terms of Interacting Partners?
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