MBNL1 and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MBNL1	AEN
Description		muscleblind like splicing regulator 1	apoptosis enhancing nuclease
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Regulatory Region RNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Metal Ion Binding	Nucleic Acid Binding Exonuclease Activity Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Nervous System Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blond vs. brown/black hair color ( 30531825) End-stage renal disease ( 29885931) Fasting glucose ( 34059833) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Infantile hypertrophic pyloric stenosis ( 22306654) Liver enzyme levels (alanine transaminase) ( 33972514) Male-pattern baldness ( 27182965) Prostate cancer ( 29892016) Type 2 diabetes ( 30054458 30297969 32499647) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) White blood cell count ( 32888494)	Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: ABI3BP AEN APP BIN1 DAB1 FBXO7 IDH3A ITSN2 TLE5 ZNHIT3	38 interacting genes: AAMP CRTC3 EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473
Entrez ID		4154	64782
HPRD ID		07355	08573
Ensembl ID		ENSG00000152601	ENSG00000181026
Uniprot IDs		Q86VM6 Q9NR56	Q8WTP8
PDB IDs		3D2N 3D2Q 3D2S 5U6H 5U6L 5U9B
Enriched GO Terms of Interacting Partners?
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