AEN and KHDRBS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		AEN	KHDRBS2
Description		apoptosis enhancing nuclease	KH RNA binding domain containing, signal transduction associated 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus Nucleoplasm
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		38 interacting genes: AAMP CRTC3 EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473	47 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPK HNRNPLL KHDRBS3 LINC01018 LMNTD2 LNX1 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM14 RBM3 RBMX RFC3 SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837
Entrez ID		64782	202559
HPRD ID		08573	13775
Ensembl ID		ENSG00000181026	ENSG00000112232
Uniprot IDs		Q8WTP8	A0A6Q8PGH5 Q5VWX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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