MAGEA6 and ATP6V1G1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MAGEA6	ATP6V1G1
Description		MAGE family member A6	ATPase H+ transporting V1 subunit G1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Histone Deacetylase Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy	Cellular Iron Ion Homeostasis Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)	Bone mineral density (hip) and age at menarche ( 26312577) Bone mineral density (spine) and age at menarche ( 26312577)
Interacting Genes		75 interacting genes: ACOT7 ACTN3 AKAP6 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FAM214A FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76	14 interacting genes: AP2B1 APP ATP6V1E1 ATP6V1E2 BCL2L11 GOLGA2 GOLGA6L9 GORASP2 LDOC1 LHX3 MAGEA6 NTAQ1 PNMA1 UBQLN2
Entrez ID		4105	9550
HPRD ID		02168	06294
Ensembl ID		ENSG00000197172	ENSG00000136888
Uniprot IDs		P43360	A0A024R883 O75348
PDB IDs			6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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