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ATP6V1G1

Description ATPase H+ transporting V1 subunit G1
Image
GO Annotations Cellular Component
  • Vacuolar Proton-transporting V-type ATPase, V1 Domain
  • Lysosomal Membrane
  • Cytosol
  • Plasma Membrane
  • Apical Plasma Membrane
  • Vacuolar Proton-transporting V-type ATPase Complex
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • Proton-transporting ATPase Activity, Rotational Mechanism
  • ATPase Binding
Biological Process
  • Cellular Iron Ion Homeostasis
  • Regulation Of Macroautophagy
  • Cellular Response To Increased Oxygen Levels
  • Proton Transmembrane Transport
Pathways
  • ROS and RNS production in phagocytes
  • Insulin receptor recycling
  • Transferrin endocytosis and recycling
  • Amino acids regulate mTORC1
  • Ion channel transport
Drugs
  • Tiludronic acid
Diseases
GWAS
  • Bone mineral density (hip) and age at menarche ( 26312577)
  • Bone mineral density (spine) and age at menarche ( 26312577)
Interacting Genes 14 interacting genes: AP2B1 APP ATP6V1E1 ATP6V1E2 BCL2L11 GOLGA2 GOLGA6L9 GORASP2 LDOC1 LHX3 MAGEA6 NTAQ1 PNMA1 UBQLN2
Entrez ID 9550
HPRD ID 06294
Ensembl ID ENSG00000136888
Uniprot IDs A0A024R883 O75348
PDB IDs 6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025