MAF and FOSL1

Number of citations of the paper that reports this interaction (PubMedID 23661758)
66

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MAF	FOSL1
Description		MAF bZIP transcription factor	FOS like 1, AP-1 transcription factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Chromatin Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Inner Ear Development Lens Fiber Cell Differentiation	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of DNA-binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Initiation
Pathways		RUNX2 regulates osteoblast differentiation	NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Alzheimer's disease (late onset) ( 30820047) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 33547301 34315874) Colorectal cancer ( 30529582 31826910) Depressive symptoms (SSRI exposure interaction) ( 25649181) Estimated glomerular filtration rate ( 31015462) Height ( 20668459) High density lipoprotein cholesterol levels ( 33339817) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lysophosphatidylcholine levels ( 31551469) Macular thickness ( 30535121) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602 21833088) Obesity ( 19151714) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Refractive error ( 32231278) Renal function-related traits (urea) ( 22797727) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 33547301 29403010 33339817) Serum thyroid-stimulating hormone levels ( 24852370) Serum uric acid levels ( 30993211) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293) Triglyceride levels ( 32203549) Urate levels ( 31985003 23263486) Vitamin C levels ( 33203707)	Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		17 interacting genes: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB NEU1 SMARCA5 SOX9 UBE2O USF2	31 interacting genes: ATF2 ATF3 ATF4 ATXN1 BATF3 CALCOCO1 CCDC120 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 ERCC6 GCC1 JUN JUNB KIFC3 KPNA1 LDOC1 MAF MAFB NME7 PARVG PIN1 TAB2 TRIM24 USF1 VEGFB WFDC1
Entrez ID		4094	8061
HPRD ID		01518	00643
Ensembl ID		ENSG00000178573	ENSG00000175592
Uniprot IDs		H3BP11 O75444	A0A0S2Z595 E9PKL5 E9PPX2 P15407
PDB IDs
Enriched GO Terms of Interacting Partners?
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