SMAD1 and DLC1

  • Number of citations of the paper that reports this interaction (PubMedID 24412244)
  • 2
  • Data Source:
  • BioGRID (two hybrid)

SMAD1

DLC1

Description SMAD family member 1 DLC1 Rho GTPase activating protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • HDL cholesterol levels ( 32203549)
  • Hemoglobin ( 32888494)
  • Lung function (FEV1) ( 30061609)
  • Malaria ( 31844061)
  • Midgestational cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Panic disorder ( 31712720)
  • Red cell distribution width ( 32888494)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Apolipoprotein A1 levels ( 32203549)
  • Attention deficit hyperactivity disorder ( 30563984)
  • Bipolar disorder ( 22688191)
  • Emphysema imaging phenotypes ( 26030696)
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Familial hepatitis B virus-related hepatocellular carcinoma ( 28662289)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • Gestational age at birth (child effect) ( 31194736)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Heel bone mineral density ( 30598549)
  • Height ( 31562340)
  • Intraocular pressure ( 29617998)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Late-onset Alzheimer's disease ( 27770636)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Lung adenocarcinoma ( 28604730)
  • Metabolite levels ( 23823483)
  • Nicotine dependence symptom count ( 25555482)
  • Nose size ( 27182965)
  • Obesity-related traits ( 23251661)
  • Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
  • Percentage gas trapping ( 26030696)
  • Platelet distribution width ( 32888494)
  • PR interval ( 32439900)
  • Refractive error ( 32231278)
  • Smoking initiation (ever regular vs never regular) ( 31089300)
  • Waist-hip ratio ( 28552196)
Interacting Genes 161 interacting genes: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APC APP AR ARHGEF6 ARL4D AXIN2 BMPR1A BTBD2 BTG2 BUB1 CAMSAP1 CCND1 CDK7 CDK9 CHMP3 CILK1 COL4A1 CTNNA1 DACH1 DLC1 DNMT3L DVL1 ECSIT EIF2AK4 ELP3 EP300 EPN2 ERBB2 ERBIN EWSR1 FBXL12 FBXO30 FBXW7 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 LMNA MAP2K3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MLH1 MLH3 MRTFB MSH2 MUTYH NAT9 NEDD4 NEDD9 NEUROG1 NFE2L2 NKX3-2 NOTCH2 NRAS OAZ1 OAZ3 PAK1 PARD3 PDGFRL PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PTPN12 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STK11 STUB1 SUV39H1 TCF20 TET2 TGFBR1 TLR2 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4 36 interacting genes: ACOT7 AKT1 AOPEP BAAT CCDC180 CDC14B CORO2A CTSV FANCC FBP2 HEMGN HSD17B3 MAPK3 PFKM PKM PPP3R2 PTEN RANGAP1 RASA1 RHOA RPS6KA1 SFRP4 SMAD1 SOX7 STX17 TDRD7 TGFB1 TMEFF1 TMEM129 TMOD1 TNS2 TRMO USP4 XPA ZNF189 ZNF510
Entrez ID 4086 10395
HPRD ID 03356 05035
Ensembl ID ENSG00000170365 ENSG00000164741
Uniprot IDs Q15797 A8K119 Q96QB1
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1 3Q47 3Q4A 5ZOK 2DKY 2GYT 2KAP 2LOZ 3KUQ 5FZT
Enriched GO Terms of Interacting Partners?
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