MXD1 and SAP30

Number of citations of the paper that reports this interaction (PubMedID 7889570)
198

Data Source:
HPRD (in vivo, in vitro)

		MXD1	SAP30
Description		MAX dimerization protein 1	Sin3A associated protein 30
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Mitochondrion Cytosol	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Skeletal Muscle Cell Differentiation Modulation By Host Of Symbiont Transcription
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		20 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MOGS MYC MYCL MYCN PML PRAM1 REL RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	27 interacting genes: BRMS1 BRMS1L CIR1 CYTOR GABBR2 H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		4084	8819
HPRD ID		02487	04540
Ensembl ID		ENSG00000059728	ENSG00000164105
Uniprot IDs		B7ZLI7 Q05195	O75446
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q	2KDP
Enriched GO Terms of Interacting Partners?
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