TM4SF1 and ANPEP

Number of citations of the paper that reports this interaction (PubMedID 15812828)
32

Data Source:
HPRD (in vivo, in vitro)

		TM4SF1	ANPEP
Description		transmembrane 4 L six family member 1	alanyl aminopeptidase, membrane
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Space Cytoplasm Lysosomal Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Virus Receptor Activity Aminopeptidase Activity Metallopeptidase Activity Zinc Ion Binding Signaling Receptor Activity Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Biological_process	Angiogenesis Proteolysis Signal Transduction Regulation Of Blood Pressure Cell Differentiation Peptide Catabolic Process Viral Entry Into Host Cell
Pathways			Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation
Drugs			Ezetimibe Icatibant
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Ischemic stroke (large artery atherosclerosis) ( 29531354)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Blood metabolite levels ( 24816252) Gallstone disease ( 30504769) Intraocular pressure ( 29617998) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		9 interacting genes: ANPEP ATP1B1 BRD4 DDR1 DNAJA1 HSPA8 SDCBP2 SLC13A1 TUBA4A	2 interacting genes: MTDH TM4SF1
Entrez ID		4071	290
HPRD ID		01854	01055
Ensembl ID		ENSG00000169908	ENSG00000166825
Uniprot IDs		P30408	A0A024RC61 P15144 Q59E93
PDB IDs			4FYQ 4FYR 4FYS 4FYT 5LHD 6ATK 6U7E 6U7F 6U7G 7AEW
Enriched GO Terms of Interacting Partners?
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