ANPEP and TM4SF1

Number of citations of the paper that reports this interaction (PubMedID 15812828)
32

Data Source:
HPRD (in vivo, in vitro)

		ANPEP	TM4SF1
Description		alanyl aminopeptidase, membrane	transmembrane 4 L six family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Lysosomal Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Extracellular Exosome	Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Aminopeptidase Activity Metallopeptidase Activity Zinc Ion Binding Signaling Receptor Activity Peptide Binding Metalloaminopeptidase Activity	Molecular_function Protein Binding
	Biological Process	Angiogenesis Proteolysis Signal Transduction Regulation Of Blood Pressure Cell Differentiation Peptide Catabolic Process Viral Entry Into Host Cell	Biological_process
Pathways		Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation
Drugs		Ezetimibe Icatibant
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Blood metabolite levels ( 24816252) Gallstone disease ( 30504769) Intraocular pressure ( 29617998) Liver enzyme levels (alanine transaminase) ( 33972514)	Alanine aminotransferase levels ( 33547301) Ischemic stroke (large artery atherosclerosis) ( 29531354)
Interacting Genes		2 interacting genes: MTDH TM4SF1	9 interacting genes: ANPEP ATP1B1 BRD4 DDR1 DNAJA1 HSPA8 SDCBP2 SLC13A1 TUBA4A
Entrez ID		290	4071
HPRD ID		01055	01854
Ensembl ID		ENSG00000166825	ENSG00000169908
Uniprot IDs		A0A024RC61 P15144 Q59E93	P30408
PDB IDs		4FYQ 4FYR 4FYS 4FYT 5LHD 6ATK 6U7E 6U7F 6U7G 7AEW
Enriched GO Terms of Interacting Partners?
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