MIR199A1 and FAM98A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR199A1	FAM98A
Description		microRNA 199a-1	family with sequence similarity 98 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	TRNA-splicing Ligase Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Protein Methyltransferase Activity
	Biological Process	Re-entry Into Mitotic Cell Cycle Negative Regulation Of Receptor Internalization Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of TOR Signaling Negative Regulation Of Hepatocyte Growth Factor Production Gene Silencing By MiRNA Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Myoblast Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Lung Blood Pressure Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Metallopeptidase Activity Positive Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Connective Tissue Replacement Positive Regulation Of Connective Tissue Replacement Positive Regulation Of Myoblast Proliferation	Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Lysosome Localization Positive Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756) Hypertension (young onset) ( 19421330) IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7) ( 26741287) Irritable bowel syndrome ( 29626450) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933) Perceived intensity of aspartame ( 31005972) Response to antidepressants in depression ( 27622933) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		83 interacting genes: AIMP1 AIMP2 C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SAFB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3	67 interacting genes: ATL2 MIR1-2 MIR106A MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT RTRAF YIPF4
Entrez ID		406976	25940
HPRD ID			16808
Ensembl ID		ENSG00000207752	ENSG00000119812
Uniprot IDs			B4DT23 I6L9E8 Q8NCA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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