FAM98A and RTRAF

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, biochemical, affinity chromatography technology)

		FAM98A	RTRAF
Description		family with sequence similarity 98 member A	RNA transcription, translation and transport factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-splicing Ligase Complex	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm TRNA-splicing Ligase Complex Mitotic Spindle
	Molecular Function	RNA Binding Protein Binding Protein Methyltransferase Activity	RNA Polymerase II Complex Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Lysosome Localization Positive Regulation Of Ruffle Assembly	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Negative Regulation Of Protein Kinase Activity Positive Regulation Of Transcription By RNA Polymerase II RNA Transport
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Hypertension (young onset) ( 19421330) IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7) ( 26741287) Irritable bowel syndrome ( 29626450) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933) Perceived intensity of aspartame ( 31005972) Response to antidepressants in depression ( 27622933) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		67 interacting genes: ATL2 MIR1-2 MIR106A MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT RTRAF YIPF4	7 interacting genes: DISC1 FAM98A GLP1R MTNR1A NIN PSORS1C2 TAOK2
Entrez ID		25940	51637
HPRD ID		16808	16615
Ensembl ID		ENSG00000119812	ENSG00000087302
Uniprot IDs		B4DT23 I6L9E8 Q8NCA5	Q549M8 Q9Y224
PDB IDs
Enriched GO Terms of Interacting Partners?
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