ARL3 and ARL2BP

Number of citations of the paper that reports this interaction (PubMedID 11303027)
48

Data Source:
HPRD (two hybrid, in vitro)

		ARL3	ARL2BP
Description		ADP ribosylation factor like GTPase 3	ADP ribosylation factor like GTPase 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton Midbody Photoreceptor Connecting Cilium Extracellular Exosome	Nucleus Mitochondrial Intermembrane Space Mitochondrial Matrix Centrosome Spindle Cytosol Cilium Midbody
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding GTPase Activating Protein Binding	Transcription Coactivator Activity Protein Binding GTPase Regulator Activity
	Biological Process	Mitotic Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Protein Transport Positive Regulation Of Microtubule Polymerization Intraciliary Transport Photoreceptor Cell Development Cilium Assembly Protein Localization To Cilium Protein Localization To Ciliary Membrane	Signal Transduction Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Maintenance Of Protein Location In Nucleus
Pathways		Trafficking of myristoylated proteins to the cilium	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs		2-(N-morpholino)ethanesulfonic acid Guanosine-5'-Diphosphate
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30487518) Hip circumference adjusted for BMI ( 34021172) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 27922604) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		12 interacting genes: ARL2BP GOLGA4 LRIF1 PDE6D PTEN RP2 TBL1X TLE1 TP53 TUBA1A UBR1 UNC119	8 interacting genes: ARL2 ARL3 CAMK2D CFAP20 DDX10 FLT1 MPP3 RAC1
Entrez ID		403	23568
HPRD ID		05260	09808
Ensembl ID		ENSG00000138175	ENSG00000102931
Uniprot IDs		P36405	A0A024R6U9 Q9Y2Y0
PDB IDs			2K9A 3DOE 3DOF
Enriched GO Terms of Interacting Partners?
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