LOX and DHDDS

Number of citations of the paper that reports this interaction (PubMedID 15110773)
6

Data Source:
HPRD (two hybrid)

		LOX	DHDDS
Description		lysyl oxidase	dehydrodolichyl diphosphate synthase subunit
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Dehydrodolichyl Diphosphate Synthase Complex
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding	Polyprenyltransferase Activity Protein Binding Dehydrodolichyl Diphosphate Synthase Activity Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Response To Xenobiotic Stimulus Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Cell Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Dolichyl Diphosphate Biosynthetic Process Polyprenol Biosynthetic Process
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	Synthesis of Dolichyl-phosphate Defective DHDDS causes retinitis pigmentosa 59
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Waist circumference adjusted for body mass index ( 34021172) Youthful appearance (self-reported) ( 32339537)	Caffeine consumption from tea ( 33287642) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		15 interacting genes: DHDDS DPT ELN EYA2 GAP43 H1-1 H1-5 H2BC11 H2BC21 MYL4 NAMPT RAF1 SNX24 ZNF202 ZNF608	4 interacting genes: LOX MT-ND1 NPC2 VRK2
Entrez ID		4015	79947
HPRD ID		01087	12183
Ensembl ID		ENSG00000113083	ENSG00000117682
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	Q86SQ9
PDB IDs			6W2L 6Z1N
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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