LIMK1 and MAPKAPK2

  • Number of citations of the paper that reports this interaction (PubMedID 16456544)
  • 61
  • Data Source:
  • BioGRID (enzymatic study)

LIMK1

MAPKAPK2

Description LIM domain kinase 1 MAPK activated protein kinase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulse pressure ( 30224653)
  • Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 32 interacting genes: ABCA1 APP ARRB1 ARRB2 BMPR2 C22orf15 C5 CDC42BPA CDKN1C CFL1 CFL2 FBXO7 H1-1 LATS1 LIMK2 MAPK14 MAPKAPK2 MBP MFHAS1 NRG1 PAK1 PAK2 PAK4 PAK6 PXN RLIM ROCK1 SELENOS SRPK1 SSH3 WASHC1 YWHAZ 42 interacting genes: AGO2 AKT1 ALOX5 ARPC5 ATF1 BAG2 BCL2L1 BECN1 CDC25B CEP131 CREB1 DDX5 DES EEF2K ETV1 HNRNPA0 HSF1 HSPB1 LIMK1 LSP1 MAP2K6 MAPK14 MAPK3 MDM2 PABPC1 PARN PHC2 PIAS2 RCSD1 SHC1 SRF STAT3 TCF3 TH TRIM28 TRIM29 TSC2 UBE2J1 WASF1 YWHAZ ZFP36 ZFP36L1
Entrez ID 3984 9261
HPRD ID 03210 11882
Ensembl ID ENSG00000106683 ENSG00000162889
Uniprot IDs P53667 P49137
PDB IDs 3S95 5HVJ 5HVK 5L6W 5NXC 6WLY 7ATS 7ATU 1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3A2C 3FPM 3FYJ 3FYK 3GOK 3KA0 3KC3 3KGA 3M2W 3M42 3R2B 3R2Y 3R30 3WI6 4TYH 6TCA
Enriched GO Terms of Interacting Partners?
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