LIMK1 and ROCK1

  • Number of citations of the paper that reports this interaction (PubMedID 10436159)
  • 507
  • Data Source:
  • HPRD (in vivo, in vitro)

LIMK1

ROCK1

Description LIM domain kinase 1 Rho associated coiled-coil containing protein kinase 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulse pressure ( 30224653)
  • Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
  • Youthful appearance (self-reported) ( 32339537)
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Lysophosphatidylcholine levels ( 31551469)
  • Telomere length ( 30185882)
Interacting Genes 32 interacting genes: ABCA1 APP ARRB1 ARRB2 BMPR2 C22orf15 C5 CDC42BPA CDKN1C CFL1 CFL2 FBXO7 H1-1 LATS1 LIMK2 MAPK14 MAPKAPK2 MBP MFHAS1 NRG1 PAK1 PAK2 PAK4 PAK6 PXN RLIM ROCK1 SELENOS SRPK1 SSH3 WASHC1 YWHAZ 37 interacting genes: ADD1 ARHGAP24 CASP3 CASP7 CDC25A CDC34 CFAP206 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LINC00452 LMO2 MAGEB4 MLC1 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TPPP TRIM15 TSG101 UBE2T VIM
Entrez ID 3984 6093
HPRD ID 03210 03414
Ensembl ID ENSG00000106683 ENSG00000067900
Uniprot IDs P53667 Q13464
PDB IDs 3S95 5HVJ 5HVK 5L6W 5NXC 6WLY 7ATS 7ATU 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S 4L2W 4W7P 4YVC 4YVE 5BML 5F5P 5HVU 5KKS 5KKT 5UZJ 5WNE 5WNF 5WNG 5WNH 6E9W 7JOU
Enriched GO Terms of Interacting Partners?
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