KRT17 and EVL

		KRT17	EVL
Description		keratin 17	Enah/Vasp-like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Intermediate Filament Cytoskeleton Cell Periphery	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium
	Molecular Function	Structural Molecule Activity Protein Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways		Keratinization Formation of the cornified envelope	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes		12 interacting genes: APC CCDC85B EGFR EVL HRAS KDM1A KRT6A KRT7 KRT72 SNAPIN TRIM69 ZDHHC17	45 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP ATG2B BDKRB1 BEGAIN C14orf132 CKB CRKL DNMBP ENAH F11R FXR1 FXR2 FYB1 FYN GSKIP HCK HTT KRT17 KRT34 LRP1B LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		3872	51466
HPRD ID		01019	10942
Ensembl ID		ENSG00000128422	ENSG00000196405
Uniprot IDs		Q04695 Q14666	A0A024R6K5 Q9UI08
PDB IDs
Enriched GO Terms of Interacting Partners?
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