ITIH4 and TP63

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

ITIH4

TP63

Description inter-alpha-trypsin inhibitor heavy chain 4 tumor protein p63
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety/tension (special factor of neuroticism) ( 30867560)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 21926972 31043756)
  • Blood protein levels ( 30072576)
  • Body mass index ( 28552196 24861553)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Immune reponse to smallpox (secreted IL-2) ( 22610502)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Manganese levels ( 26025379)
  • Neurological blood protein biomarker levels ( 31320639)
  • Parkinson's disease ( 28892059)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Schizophrenia ( 25056061 21926974 29483656 23974872)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Ulcerative colitis ( 23128233)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 4 interacting genes: DNAJC1 GRB2 KLK1 TP63 41 interacting genes: BAG6 BTRC CCNC CDC20 CDKN2A COPS6 CSNK2A1 CSNK2A2 CSNK2B DAXX EMX1 EP300 GCGR GRB2 HIPK2 HNRNPAB HP HPX ITCH ITIH4 KAT2B MCRS1 MDM4 NIPSNAP3A ORM1 PELI1 PELI2 PIN1 PINX1 PML PPP1R13B PPP2R5A RACK1 RCHY1 SCAF4 SLC35A3 TP53 TP73 UBASH3A UBE2I WT1
Entrez ID 3700 8626
HPRD ID 02781 04469
Ensembl ID ENSG00000055955 ENSG00000073282
Uniprot IDs B2RMS9 B7ZKJ8 Q14624 A0A0S2Z4N5 A0A0S2Z4N6 A0A141PNN3 A0A141PNN4 B7Z8X6 C9D7D0 Q9H3D4
PDB IDs 1RG6 2NB1 2RMN 2Y9T 2Y9U 3QYM 3QYN 3US0 3US1 3US2 3ZY0 3ZY1 4A9Z 6FGN 6RU6 6RU7 6RU8
Enriched GO Terms of Interacting Partners?
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