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ITGAV and AZGP1
Number of citations of the paper that reports this interaction (PubMedID
9813179
)
0
Data Source:
HPRD
(in vitro)
ITGAV
AZGP1
Description
integrin subunit alpha V
alpha-2-glycoprotein 1, zinc-binding
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Membrane
Lamellipodium Membrane
Filopodium Membrane
Microvillus Membrane
Ruffle Membrane
Integrin Alphav-beta3 Complex
Integrin Alphav-beta5 Complex
Integrin Alphav-beta6 Complex
Integrin Alphav-beta8 Complex
Specific Granule Membrane
Alphav-beta3 Integrin-PKCalpha Complex
Alphav-beta3 Integrin-IGF-1-IGF1R Complex
Alphav-beta3 Integrin-HMGB1 Complex
Phagocytic Vesicle
Extracellular Exosome
Extracellular Region
Extracellular Space
Nucleus
External Side Of Plasma Membrane
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Virus Receptor Activity
Opsonin Binding
Fibronectin Binding
Protease Binding
Protein Kinase C Binding
Integrin Binding
Voltage-gated Calcium Channel Activity
Protein Binding
Coreceptor Activity
Fibroblast Growth Factor Binding
C-X3-C Chemokine Binding
Insulin-like Growth Factor I Binding
Neuregulin Binding
Metal Ion Binding
Transforming Growth Factor Beta Binding
Extracellular Matrix Binding
Extracellular Matrix Protein Binding
Ribonuclease Activity
Protein Binding
Protein Transmembrane Transporter Activity
Biological Process
Angiogenesis
Vasculogenesis
Cell Adhesion
Cell-matrix Adhesion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Lipid Storage
Cell Migration
Positive Regulation Of Cell Migration
Cell-substrate Adhesion
Negative Regulation Of Lipid Transport
Cell Adhesion Mediated By Integrin
Positive Regulation Of Osteoblast Proliferation
Heterotypic Cell-cell Adhesion
Substrate Adhesion-dependent Cell Spreading
Endodermal Cell Differentiation
Apolipoprotein A-I-mediated Signaling Pathway
Apoptotic Cell Clearance
Positive Regulation Of Cell Adhesion
Viral Entry Into Host Cell
Negative Regulation Of Lipoprotein Metabolic Process
Regulation Of Phagocytosis
Negative Chemotaxis
Positive Regulation Of Small GTPase Mediated Signal Transduction
ERK1 And ERK2 Cascade
Calcium Ion Transmembrane Transport
Transforming Growth Factor Beta Production
Entry Into Host Cell By A Symbiont-containing Vacuole
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Transforming Growth Factor Beta Activation
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Low-density Lipoprotein Receptor Activity
Negative Regulation Of Entry Of Bacterium Into Host Cell
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste
Retina Homeostasis
Positive Regulation Of T Cell Mediated Cytotoxicity
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
Immune Response
Cell Adhesion
Negative Regulation Of Cell Population Proliferation
Protein Transmembrane Transport
RNA Phosphodiester Bond Hydrolysis
Pathways
Cross-presentation of particulate exogenous antigens (phagosomes)
Elastic fibre formation
PECAM1 interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Integrin cell surface interactions
Laminin interactions
Syndecan interactions
Syndecan interactions
ECM proteoglycans
VEGFA-VEGFR2 Pathway
Signal transduction by L1
Neutrophil degranulation
Miscellaneous transport and binding events
Drugs
Antithymocyte immunoglobulin (rabbit)
Levothyroxine
N-acetyl-alpha-neuraminic acid
Copper
Diseases
GWAS
Asthma (
32296059
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Left-handedness (
32989287
)
Lung function (FEV1/FVC) (
30804560
)
Microalbuminuria (
26631737
)
Urinary albumin-to-creatinine ratio (
26631737
)
Urinary albumin-to-creatinine ratio in non-diabetics (
26631737
)
Brain morphology (MOSTest) (
32665545
)
Red blood cell count (
27863252
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
33 interacting genes:
ADAM9
ANGPTL3
AUP1
AZGP1
CALR
CCN1
CCN3
CD47
EDIL3
F2R
ICAM4
ITGB1
ITGB3
ITGB5
ITGB6
ITGB8
L1CAM
LGALS3BP
MAPK3
MMP14
MMP2
NID1
P2RY2
PAK4
PDGFRA
PLA2G2A
PLP1
PTK2
PXN
SPP1
TGFB1
THY1
UBC
5 interacting genes:
ABCC1
ITGAV
NUF2
SHBG
UBQLN2
Entrez ID
3685
563
HPRD ID
01903
01910
Ensembl ID
ENSG00000138448
ENSG00000160862
Uniprot IDs
L7RXH0
P06756
A0A140VK00
P25311
PDB IDs
1JV2
1L5G
1M1X
1U8C
3IJE
4G1E
4G1M
4MMX
4MMY
4MMZ
4O02
4UM8
4UM9
5FFG
5FFO
5NEM
5NER
5NET
5NEU
6AVQ
6AVR
6AVU
6DJP
6MK0
6MSL
6MSU
6NAJ
6OM1
6OM2
6UJA
6UJB
6UJC
1T7V
1T7W
1T7X
1T7Y
1T7Z
1T80
1ZAG
3ES6
6R2U
Enriched GO Terms of Interacting Partners
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