AQP4 and AP3M1

Number of citations of the paper that reports this interaction (PubMedID 11742978)
41

Data Source:
HPRD (in vitro)

		AQP4	AP3M1
Description		aquaporin 4	adaptor related protein complex 3 subunit mu 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Basolateral Plasma Membrane Sarcolemma Astrocyte End-foot	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Axon Cytoplasm
	Molecular Function	Protein Binding Water Channel Activity	Protein Binding Small GTPase Binding
	Biological Process	Renal Water Homeostasis Water Transport Cellular Water Homeostasis Water Homeostasis Multicellular Organismal Water Homeostasis Protein Homotetramerization Transmembrane Transport Cellular Response To Interferon-gamma Cerebrospinal Fluid Circulation	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins	Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Metabolite levels ( 23823483)	Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: AP2M1 AP3M1 CREB3 CSNK2A1 CSNK2A2 GJA8 HPCAL4	15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9
Entrez ID		361	26985
HPRD ID		02631	16496
Ensembl ID		ENSG00000171885	ENSG00000185009
Uniprot IDs		A0A5F9ZHR4 F1DSG4 P55087 V9PBN7	A0A024QZR5 B4DRN6 Q9Y2T2
PDB IDs		3GD8
Enriched GO Terms of Interacting Partners?
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