IL16 and KCNJ2

  • Number of citations of the paper that reports this interaction (PubMedID 10479680)
  • 20
  • Data Source:
  • HPRD (two hybrid, in vivo)

IL16

KCNJ2

Description interleukin 16 potassium inwardly rectifying channel subfamily J member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis (severe) ( 24023777)
  • Alanine aminotransferase levels ( 33547301)
  • Aspartate aminotransferase levels ( 33547301)
  • Atrial fibrillation ( 29892015)
  • Birth weight ( 31043758)
  • Chin dimples ( 27182965)
  • Dentures ( 31235808)
  • Depressive episodes in bipolar disorder ( 26297903)
  • Early cardiac repolarization ( 22342860)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Electrocardiographic traits (multivariate) ( 32602732)
  • Formal thought disorder in schizophrenia ( 22648509)
  • HDL cholesterol levels ( 32203549 32109663)
  • Hip circumference adjusted for BMI ( 25673412)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (forced vital capacity) ( 24929828)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328 20195514)
  • Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
  • Prudent dietary pattern ( 28644415)
  • Pulmonary function (smoking interaction) ( 23284291)
  • QT interval ( 30679814 24952745 19305409 29874175)
  • Refractive error ( 23396134)
  • Renal overload gout ( 32238385)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • Thyrotoxic hypokalemic periodic paralysis ( 22863731 22399142)
  • Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
  • Thyrotoxic periodic paralysis ( 33105104)
  • TPE interval (response to exercise) ( 32386560)
  • TPE interval (resting) ( 32386560)
  • Triglyceride levels ( 32203549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 109 interacting genes: ANXA6 BLZF1 BOLA2 BOLA2B CALCOCO2 CAMK1 CARD10 CASP3 CCDC184 CCDC33 CD4 CDK1 CEP72 CSNK2A1 CSNK2A2 CYSRT1 DMRTB1 DUSP7 EFEMP2 FAM124A FHL2 FHL5 FTO GABPB1 GOLGA2 GOLGA6L9 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 HOMEZ HOOK2 HSF2BP JAKMIP1 KANK2 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KCTD9 KDM1A KIF16B KIFC3 KRT31 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP3-1 L3MBTL3 LGALS14 LMO3 LNX1 LNX2 MBD3L1 MID2 MIER2 MTUS2 MYOG NOXA1 NTAQ1 OIP5 PCSK6 PDLIM7 PFDN5 PICK1 PPP1R12A PPP1R12B PPP1R12C PPP1R16A PRDM6 PRR13 PSTPIP1 RAPGEF2 RBCK1 RNF144B SERTAD3 SMARCB1 SOHLH1 SPRED1 SUV39H1 TEPSIN TFIP11 TRIB3 TRIM23 TRIM27 TRIM42 TRIP6 UBXN11 USHBP1 WWTR1 ZBTB39 ZIM2 ZNF143 ZNF165 ZNF474 ZNF526 ZNF572 ZNF581 ZNF620 ZNF774 ZNF777 ZNF835 ZNRD2 ZRANB1 21 interacting genes: AKAP5 ARL13B CASK DLG1 DLG2 DLG3 DLG4 FLNA IL16 KCNJ11 KCNJ15 KCNJ16 KCNJ18 KCNJ4 KCNJ8 PATJ SDC3 SDCBP SEC22A TRAK2 UTP18
Entrez ID 3603 3759
HPRD ID 04329 02815
Ensembl ID ENSG00000172349 ENSG00000123700
Uniprot IDs Q14005 Q9UME6 P63252
PDB IDs 1I16 1X6D 5FB8 6SPZ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?