APOD and TMEM45B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		APOD	TMEM45B
Description		apolipoprotein D	transmembrane protein 45B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Cytosolic Ribosome Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Lipid Transporter Activity Protein Binding Cholesterol Binding	Protein Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Glucose Metabolic Process Lipid Metabolic Process Lipid Transport Brain Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Tissue Regeneration Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Negative Regulation Of Focal Adhesion Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of T Cell Migration
Pathways		Transport of fatty acids NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs		Vitamin A Copper
Diseases
GWAS		HDL cholesterol levels ( 32203549)	Breast cancer ( 22383897) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Obsessive-compulsive traits ( 33531474) Serum metabolite levels ( 33031748) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Type 2 diabetes ( 22238593)
Interacting Genes		51 interacting genes: AIG1 APH1A APOA2 AQP9 ATP6V0B ATP6V0E1 BCL2L13 BIK CD53 CD79A CLDN7 CLEC10A CPLX4 CREB3 CREB3L1 ERGIC3 EVI2B FAM209A FFAR2 FKBP7 FPR2 GDAP1 GJA8 GORAB GPR151 GPR42 GPX8 KCNJ6 KIR2DL3 LEPR LMNA MFF MGST3 MTERF2 MTIF3 NCAPH2 PDZK1IP1 POLR2M RHBDL1 SHBG SIGLECL1 SLC10A6 SLC35C2 TEX29 TMEM237 TMEM31 TMEM45B TMEM52B TMEM79 VAPA VSIR	41 interacting genes: ANKRD46 APOD APOL2 AQP1 BMP10 C3orf52 C4orf3 CACNG1 CDS2 CYB561D2 DOLK FAM3C FKBP8 GIMAP1 INSIG2 LAT NSG1 PLN PLP1 PLPP4 SEC22A SEC23A SMAGP SMIM1 SNORC SYNGR1 TINAG TMEM128 TMEM218 TMEM229B TMEM243 TMEM254 TMEM60 TMEM97 TNFRSF10C TREX1 TSPAN33 UBE2G2 UPK1B VAMP5 VKORC1
Entrez ID		347	120224
HPRD ID		00134	14020
Ensembl ID		ENSG00000189058	ENSG00000151715
Uniprot IDs		P05090	Q96B21
PDB IDs		2APD 2HZQ 2HZR
Enriched GO Terms of Interacting Partners?
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