ID2 and ADD1

Number of citations of the paper that reports this interaction (PubMedID 10585876)
27

Data Source:
HPRD (in vivo, in vitro)

		ID2	ADD1
Description		inhibitor of DNA binding 2	adducin 1
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body
	Molecular Function	Protein Binding Transmembrane Transporter Binding Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Transcription Regulator Activity Transcription Regulator Inhibitor Activity	RNA Binding Actin Binding Protein Binding Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Bundle Of His Development Heart Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Lipid Metabolic Process Olfactory Bulb Development Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Enucleate Erythrocyte Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Negative Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Macrophage Differentiation Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Muscle Cell Differentiation Regulation Of Cell Cycle Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation	Actin Cytoskeleton Organization Positive Regulation Of Protein Binding Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization
Pathways		NGF-stimulated transcription	Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 34103634 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 32439900 31217584) Self-reported allergy ( 23817569)	Coffee consumption (cups per day) ( 31837886) Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124) Monocyte percentage of white cells ( 32888494)
Interacting Genes		53 interacting genes: ADD1 ASB4 ASCL4 C22orf39 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC ENKD1 FANCL FNDC11 FRS3 GATA4 GFUS HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MSGN1 MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PICK1 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TCHP TNS2 UNC119	25 interacting genes: ADD2 ATP1A1 C1orf109 CALM1 CASP3 CSNK2B FGFR3 GEMIN7 HMG20A HSF2BP HSPH1 ID2 ID3 KLHL42 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17
Entrez ID		3398	118
HPRD ID		02664	00036
Ensembl ID		ENSG00000115738	ENSG00000087274
Uniprot IDs		Q02363 Q53T66	P35611
PDB IDs		4AYA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?