AOC1 and CYB561A3

Number of citations of the paper that reports this interaction (PubMedID 21516116)
114

Data Source:
BioGRID (two hybrid)

		AOC1	CYB561A3
Description		amine oxidase copper containing 1	cytochrome b561 family member A3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Peroxisome Plasma Membrane Bicellular Tight Junction Specific Granule Lumen Extracellular Exosome	Nucleolus Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Heparin Binding Zinc Ion Binding Protein Homodimerization Activity Protein-containing Complex Binding Quinone Binding Diamine Oxidase Activity Histamine Oxidase Activity Methylputrescine Oxidase Activity Propane-1,3-diamine Oxidase Activity	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity
	Biological Process	Amine Metabolic Process Putrescine Metabolic Process Cellular Response To Copper Ion Starvation Response To Antibiotic Cellular Response To Copper Ion Cellular Response To Histamine Cellular Response To Heparin Cellular Response To Azide	Cellular Iron Ion Homeostasis Transmembrane Transport
Pathways		Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		Amiloride Calcium Diminazene
Diseases
GWAS		Anthropometric traits (multi-trait analysis) ( 30166351) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Carpal tunnel syndrome ( 30833571) Eyebrow thickness ( 26926045) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Multisite chronic pain ( 33830993) Serum alkaline phosphatase levels ( 33547301) Serum metabolite concentrations in chronic kidney disease ( 29545352) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 30297969) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		13 interacting genes: CYB561A3 DAO DAZAP2 DNM2 FGD1 FOXH1 KRTAP8-1 NTAQ1 POGZ RBPMS2 TIAL1 TLX3 ZC3H10	23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31
Entrez ID		26	220002
HPRD ID		00088	11316
Ensembl ID		ENSG00000002726	ENSG00000162144
Uniprot IDs		P19801	F5H1Q2 Q8NBI2
PDB IDs		3HI7 3HIG 3HII 3K5T 3MPH
Enriched GO Terms of Interacting Partners?
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