HTR7 and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 15086532)
40

Data Source:
HPRD (in vitro)

		HTR7	GPRASP2
Description		5-hydroxytryptamine receptor 7	G protein-coupled receptor associated sorting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Trans-Golgi Network Membrane Synapse	Nucleus Cytoplasm
	Molecular Function	G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Circadian Rhythm Blood Circulation Vasoconstriction G Protein-coupled Serotonin Receptor Signaling Pathway	Hematopoietic Stem Cell Homeostasis
Pathways		Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Ziprasidone Methysergide Cabergoline Zolmitriptan Amitriptyline Clozapine Loxapine Cyproheptadine Imipramine Chlorpromazine Haloperidol Amoxapine Lisuride Paroxetine Risperidone Epinastine Cyclobenzaprine Maprotiline Dopamine Ergoloid mesylate Bromocriptine Quetiapine Aripiprazole Chlorprothixene Paliperidone Iloperidone Lofexidine Mianserin Asenapine Amisulpride Lurasidone Vortioxetine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine SB-269970 Aripiprazole lauroxil
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		2 interacting genes: GPRASP1 GPRASP2	52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 RTL10 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688
Entrez ID		3363	114928
HPRD ID		01639	06612
Ensembl ID		ENSG00000148680	ENSG00000158301
Uniprot IDs		P34969	B3KW05 Q96D09
PDB IDs
Enriched GO Terms of Interacting Partners?
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