GPRASP2 and HRH2

Number of citations of the paper that reports this interaction (PubMedID 15086532)
40

Data Source:
HPRD (in vitro)

		GPRASP2	HRH2
Description		G protein-coupled receptor associated sorting protein 2	histamine receptor H2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Hematopoietic Stem Cell Homeostasis	Gastric Acid Secretion Immune Response G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Positive Regulation Of Vasoconstriction G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Histamine receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Betazole Amitriptyline Loxapine Cimetidine Nizatidine Epinastine Olopatadine Tolazoline Ranitidine Famotidine Methantheline Azelastine Promethazine Doxepin Aripiprazole HZT-501 Histamine Asenapine Metiamide Roxatidine acetate
Diseases
GWAS			Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 RTL10 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	2 interacting genes: GPRASP2 SLIT3
Entrez ID		114928	3274
HPRD ID		06612	00816
Ensembl ID		ENSG00000158301	ENSG00000113749
Uniprot IDs		B3KW05 Q96D09	A0A1B0GTK7 P25021
PDB IDs
Enriched GO Terms of Interacting Partners?
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