DNAJA1 and TM4SF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAJA1	TM4SF1
Description		DnaJ heat shock protein family (Hsp40) member A1	transmembrane 4 L six family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cytoplasmic Side Of Endoplasmic Reticulum Membrane	Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding ATPase Activator Activity Protein Binding ATP Binding Hsp70 Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Chaperone Binding C3HC4-type RING Finger Domain Binding	Molecular_function Protein Binding
	Biological Process	Protein Folding Response To Unfolded Protein Spermatogenesis Response To Heat Flagellated Sperm Motility Androgen Receptor Signaling Pathway Negative Regulation Of Protein Ubiquitination DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity Regulation Of Protein Transport Protein Localization To Mitochondrion Toxin Transport Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway	Biological_process
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Ischemic stroke (large artery atherosclerosis) ( 29531354)
Interacting Genes		25 interacting genes: ARL4D BCS1L BRCA1 CAV2 CD58 CDC16 CFTR ERG FZR1 HIVEP1 HMGCL HSPA8 LINC01554 LSM2 NELFCD NUDT3 OGT PAXIP1 PGR PTEN PTTG1 SUMO2 SUMO4 TM4SF1 TXN	9 interacting genes: ANPEP ATP1B1 BRD4 DDR1 DNAJA1 HSPA8 SDCBP2 SLC13A1 TUBA4A
Entrez ID		3301	4071
HPRD ID		04159	01854
Ensembl ID		ENSG00000086061	ENSG00000169908
Uniprot IDs		B7Z5C0 P31689	P30408
PDB IDs		2LO1 2M6Y 6E8M
Enriched GO Terms of Interacting Partners?
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