BIRC2 and LTBR

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

BIRC2

LTBR

Description baculoviral IAP repeat containing 2 lymphotoxin beta receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Ankylosing spondylitis ( 23749187)
  • Aspartate aminotransferase levels ( 33547301)
  • Basophil count ( 32888494)
  • Celiac disease ( 31591516)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 26192919 28067908)
  • Eosinophil percentage of white cells ( 32888494)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
  • Multiple sclerosis ( 31604244 24076602)
  • Platelet distribution width ( 32888494)
  • Plateletcrit ( 32888494 27863252)
  • Primary biliary cirrhosis ( 22961000)
  • Tonsillectomy ( 27182965 28928442)
  • White blood cell count ( 32888494)
Interacting Genes 76 interacting genes: ABHD17A BIRC5 BLK BMX BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 CBLC CD40 CDC42 CSE1L DIABLO DZIP3 E2F1 EAF2 EIF4E EXOSC5 FBXO7 FDX1 GAS1 GCC1 GFAP GLMN GSPT1 HSP90B1 HTRA2 IGF2BP1 IKBKE IKBKG JUP KDM1A LNX1 LTBR MAD1L1 MAGEA11 MAP3K2 MAP3K3 NMB NXF1 OTUB1 PACS2 PCSK9 PFN2 PPM1K RAC1 RAF1 RFC5 RHOA RIPK2 RIPK3 RIPK4 RNF181 RUNX1T1 TCAF1 TRADD TRAF1 TRAF2 TRIM34 TSG101 TSGA10 TUFT1 UBB UBC UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2J1 UBE2N UBE2Q2 UBE2S UBE2V1 UBE2W 15 interacting genes: BIRC2 DIABLO HES1 LTA LTB MTNR1B RABAC1 TNFSF14 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRIM37 ZMYND11
Entrez ID 329 4055
HPRD ID 03419 02988
Ensembl ID ENSG00000110330 ENSG00000111321
Uniprot IDs Q13490 P36941
PDB IDs 1QBH 2L9M 3D9T 3D9U 3M1D 3MUP 3OZ1 3T6P 3UW4 4EB9 4HY4 4HY5 4KMN 4LGE 4LGU 4MTI 4MU7 5M6N 6EXW 6HPR 6W74 6W7O 6W8I 1RF3 4MXW
Enriched GO Terms of Interacting Partners?
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