HOXD3 and IGFN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HOXD3	IGFN1
Description		homeobox D3	immunoglobulin like and fibronectin type III domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome Nuclear Body	Nucleus Z Disc Synapse
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell-matrix Adhesion Notch Signaling Pathway Anterior/posterior Pattern Specification Positive Regulation Of Gene Expression Thyroid Gland Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Biological_process Retina Layer Formation
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 29146897 28196072) Mucinous ovarian carcinoma ( 26075790) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Ovarian cancer ( 20852632) Pelvic organ prolapse (moderate/severe) ( 26545240)	Asthma ( 29273806) Height ( 28552196)
Interacting Genes		7 interacting genes: ALX4 DDB1 HMGB1 HOXC8 IGFN1 NFKBID SMARCD1	40 interacting genes: BANP BLZF1 C19orf54 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688
Entrez ID		3232	91156
HPRD ID		00863	16812
Ensembl ID		ENSG00000128652	ENSG00000163395
Uniprot IDs		P31249	Q86VF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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