APBA2 and ARF4

Number of citations of the paper that reports this interaction (PubMedID 12842896)
42

Data Source:
BioGRID (two hybrid)

		APBA2	ARF4
Description		amyloid beta precursor protein binding family A member 2	ADP ribosylation factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Synaptic Vesicle Dendritic Spine	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Amyloid-beta Binding Protein Binding Identical Protein Binding	GTPase Activity Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding
	Biological Process	Chemical Synaptic Transmission Nervous System Development Protein Transport	Protein ADP-ribosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Cilium Assembly Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Neurexins and neuroligins	VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Response to mTOR inhibitor (rapamycin) ( 24009623) SAPHO syndrome ( 33816493) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Temperament ( 22832960)
Interacting Genes		15 interacting genes: APP ARF3 ARF4 CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAGEB6 MAPK6 NECAB3 NRXN1 RELA STXBP1 USP20	16 interacting genes: ADRB2 APBA1 APBA2 APBA3 COPS3 EGFR HNRNPD IKBKG ITIH1 PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA SUMO2
Entrez ID		321	378
HPRD ID		04090	03107
Ensembl ID		ENSG00000034053	ENSG00000168374
Uniprot IDs		Q59G28 Q99767	P18085
PDB IDs			1Z6X
Enriched GO Terms of Interacting Partners?
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