HNRNPL and PTBP1

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical)
HPRD (in vitro, two hybrid)

		HNRNPL	PTBP1
Description		heterogeneous nuclear ribonucleoprotein L	polypyrimidine tract binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Membrane Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Intronic Binding	RNA Binding MRNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing Regulation Of RNA Splicing	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of RNA Splicing Positive Regulation Of Protein Dephosphorylation Regulation Of RNA Splicing Regulation Of Cell Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Viral Translational Initiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 34315874) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Refractive error ( 32231278) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		91 interacting genes: APEX1 CREBBP CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4 OGT PCBP2 PJA1 PTBP1 SUMO2 SUMO4	103 interacting genes: APBB1 APP CALCOCO2 CASP3 FUS H3-4 HIF1A HMGA1 HMGA2 HNRNPAB HNRNPL IL7R LINC00839 LINC01554 MARK4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NONO OGT PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 SUMO2 ZMYM2
Entrez ID		3191	5725
HPRD ID		04360	02823
Ensembl ID		ENSG00000104824	ENSG00000011304
Uniprot IDs		P14866 Q6NTA2	A0A7I2V621 P26599
PDB IDs		3R27 3TO8	1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 2N3O 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?
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