HMMR and TUBB2A

Number of citations of the paper that reports this interaction (PubMedID 10547355)
37

Data Source:
BioGRID (unspecified method)

		HMMR	TUBB2A
Description		hyaluronan mediated motility receptor	tubulin beta 2A class IIa
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane	Nucleus Cytoplasm Microtubule Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding Hyaluronic Acid Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process		Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration
Pathways		Hyaluronan uptake and degradation AURKA Activation by TPX2	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		Hyaluronic acid	CYT997 Phenethyl Isothiocyanate
Diseases
GWAS		Metabolite levels ( 23823483)	Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Red cell distribution width ( 32888494 27863252)
Interacting Genes		16 interacting genes: ACTB BACH1 CALM1 CD44 CDH13 GREB1 IL24 ITIH5 MAPK3 MORN4 NAT2 SVIL THRSP TPX2 TRIM54 TUBB2A	28 interacting genes: ACD ARL15 ARNT CHGB DISC1 DUX4 HDAC6 HGS HMMR LAMA4 LINC01554 OGT PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2
Entrez ID		3161	7280
HPRD ID		02963
Ensembl ID		ENSG00000072571	ENSG00000137267
Uniprot IDs		O75330	Q13885
PDB IDs
Enriched GO Terms of Interacting Partners?
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