HMGB2 and NCBP3

Number of citations of the paper that reports this interaction (PubMedID 29721183)
4

Data Source:
BioGRID (two hybrid)

		HMGB2	NCBP3
Description		high mobility group box 2	nuclear cap binding subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Condensed Chromosome Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Nuclear Speck RNA Cap Binding Complex
	Molecular Function	Four-way Junction DNA Binding Transcription Cis-regulatory Region Binding Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Transcription Factor Binding DNA Binding, Bending Protein Domain Specific Binding Chemoattractant Activity Non-sequence-specific DNA Binding, Bending RAGE Receptor Binding Supercoiled DNA Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Inflammatory Response To Antigenic Stimulus DNA Topological Change Double-strand Break Repair Via Nonhomologous End Joining Chromatin Organization Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Nucleus Differentiation Male Gonad Development Negative Regulation Of Gene Expression Positive Regulation Of Nuclease Activity DNA Geometric Change Response To Lipopolysaccharide Positive Regulation Of Interferon-beta Production V(D)J Recombination Positive Regulation Of DNA Binding Innate Immune Response Positive Regulation Of Innate Immune Response Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Steroid Hormone Regulation Of Neurogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Cell Chemotaxis Cellular Response To Lipopolysaccharide Regulation Of Stem Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	7-methylguanosine MRNA Capping MRNA Transport Defense Response To Virus
Pathways		Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS			Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		47 interacting genes: APEX1 APP AR ARCN1 C1QBP CACTIN CHAF1A COMMD1 CREBBP CSNK1A1 EIF1 FBXO7 FLNA GZMA GZMK H3-3A HACD3 HDLBP HMGA1 LZTS1 MIEN1 MYL6 NAP1L1 NCBP3 NEXN NOP53 NR3C1 PGR PKNOX1 POU2F1 POU2F2 POU3F1 POU5F1 PRKDC RAG1 RPS28 SAMM50 SET SNAPIN TERT TP53 TSNAX U2AF1 UHRF2 ZNF428 ZNF622 ZNF668	8 interacting genes: APP DAPK1 HMGB2 HNRNPH3 KPNA4 LENG8 LRRK2 SRPK2
Entrez ID		3148	55421
HPRD ID		01229	17116
Ensembl ID		ENSG00000164104	ENSG00000074356
Uniprot IDs		P26583	Q53F19
PDB IDs
Enriched GO Terms of Interacting Partners?
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