HBG2 and XPNPEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HBG2	XPNPEP1
Description		hemoglobin subunit gamma 2	X-prolyl aminopeptidase 1
Image
GO Annotations	Cellular Component	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Metal Ion Binding	Aminopeptidase Activity Manganese Ion Binding Protein Homodimerization Activity Metalloaminopeptidase Activity
	Biological Process	Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification	Proteolysis Bradykinin Catabolic Process
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) Hemoglobin ( 28548082) Hemoglobin levels ( 26366553) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malaria ( 31844061) Malate levels ( 31560688) Mean corpuscular hemoglobin concentration ( 32888494 28453575) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Alcohol consumption (drinks per week) ( 30643258) Biliary atresia ( 20460270) Bipolar disorder ( 31043756 28072414) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: APP CYB5R3 HBA1 HBA2 HBB HBM HBQ1 RPSA SMAD5 XPNPEP1	13 interacting genes: ANK3 DISC1 GORASP2 GSK3B HBG2 MAPK9 NUDT3 POLA2 RHOH RINT1 SUMO2 UBC UBE2D3
Entrez ID		3048	7511
HPRD ID		00792	03899
Ensembl ID		ENSG00000196565	ENSG00000108039
Uniprot IDs		D9YZU9 P69892	Q5T6H7 Q9NQW7
PDB IDs		1FDH 4MQJ 4MQK	3CTZ
Enriched GO Terms of Interacting Partners?
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