HBM and HBG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HBM	HBG2
Description		hemoglobin subunit mu	hemoglobin subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding Metal Ion Binding	Peroxidase Activity Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Metal Ion Binding
	Biological Process	Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification	Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Body mass index ( 26426971) Glycated hemoglobin levels ( 31213470) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 31217584) Hemoglobin levels ( 26366553) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 28453575 27863252) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Beta thalassemia/hemoglobin E disease ( 20183929) Hemoglobin ( 28548082) Hemoglobin levels ( 26366553) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malaria ( 31844061) Malate levels ( 31560688) Mean corpuscular hemoglobin concentration ( 32888494 28453575) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: HBB HBG2 HBZ VIRMA	10 interacting genes: APP CYB5R3 HBA1 HBA2 HBB HBM HBQ1 RPSA SMAD5 XPNPEP1
Entrez ID		3042	3048
HPRD ID			00792
Ensembl ID		ENSG00000206177	ENSG00000196565
Uniprot IDs		A0A1K0FU50 Q6B0K9	D9YZU9 P69892
PDB IDs			1FDH 4MQJ 4MQK
Enriched GO Terms of Interacting Partners?
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