H1-1 and CTCFL

Number of citations of the paper that reports this interaction (PubMedID 17048991)
80

Data Source:
BioGRID (far western blotting, pull down)

		H1-1	CTCFL
Description		H1.1 linker histone, cluster member	CCCTC-binding factor like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleosome Euchromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body
	Molecular Function	Double-stranded DNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Histone Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Nucleosome Assembly Spermatogenesis Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Cell Cycle Positive Regulation Of Gene Expression Histone Methylation DNA Methylation Involved In Gamete Generation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Histone H3-K4 Methylation
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obesity-related traits ( 23251661) Prudent dietary pattern ( 28644415) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to statin therapy ( 20339536) Triglyceride levels ( 32203549) Type 2 diabetes ( 23300278)
Interacting Genes		52 interacting genes: AEBP2 APP CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L1 NAP1L4 NASP NSD3 PAK4 PARP1 PARP3 PELP1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 RPS6KA5 SET SNCA SUZ12 TAF1 TERF1 TERF2IP TLK1	10 interacting genes: AURKA BAG6 BRCA1 H1-1 H2AC20 H3C1 PRMT7 SP1 TBP ZDHHC17
Entrez ID		3024	140690
HPRD ID		00820	09512
Ensembl ID		ENSG00000124610	ENSG00000124092
Uniprot IDs		Q02539	A6XGM0 A6XGM9 Q8NI51 V9GY73 V9GYX4
PDB IDs
Enriched GO Terms of Interacting Partners?
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