CTCFL and PRMT7

Number of citations of the paper that reports this interaction (PubMedID 17048991)
80

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		CTCFL	PRMT7
Description		CCCTC-binding factor like	protein arginine methyltransferase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body	Fibrillar Center Nucleus Nucleoplasm Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Histone Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)
	Biological Process	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Cell Cycle Positive Regulation Of Gene Expression Histone Methylation DNA Methylation Involved In Gamete Generation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Histone H3-K4 Methylation	Spliceosomal SnRNP Assembly Regulation Of Gene Expression By Genetic Imprinting Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation
Pathways			RMTs methylate histone arginines
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obesity-related traits ( 23251661) Prudent dietary pattern ( 28644415) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to statin therapy ( 20339536) Triglyceride levels ( 32203549) Type 2 diabetes ( 23300278)	Apolipoprotein A1 levels ( 33730874) Birth weight ( 31043758) Body mass index ( 28892062 25673413) Body shape index ( 34021172) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)
Interacting Genes		10 interacting genes: AURKA BAG6 BRCA1 H1-1 H2AC20 H3C1 PRMT7 SP1 TBP ZDHHC17	14 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB TRIO ZBTB24 ZNF438
Entrez ID		140690	54496
HPRD ID		09512	15174
Ensembl ID		ENSG00000124092	ENSG00000132600
Uniprot IDs		A6XGM0 A6XGM9 Q8NI51 V9GY73 V9GYX4	A0A024R726 Q9NVM4
PDB IDs
Enriched GO Terms of Interacting Partners?
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