H3-3A and SMARCA1

Number of citations of the paper that reports this interaction (PubMedID 16728976)
482

Data Source:
HPRD (in vitro)

		H3-3A	SMARCA1
Description		H3.3 histone A	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromosome, Telomeric Region Nucleosome Extracellular Region Nucleus Nucleoplasm Protein-containing Complex Extracellular Exosome	Nucleus Nucleoplasm NURF Complex Intracellular Membrane-bounded Organelle CERF Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity	DNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Transcription Factor Binding Hydrolase Activity Nucleosome Binding ATP-dependent DNA/DNA Annealing Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Positive Regulation Of Cell Growth Telomere Organization	Chromatin Remodeling Brain Development Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination Transcriptional regulation of granulopoiesis Inhibition of DNA recombination at telomere Defective pyroptosis Amyloid fiber formation Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Pulse pressure ( 27841878) Schizophrenia x sex interaction ( 34099189) Systolic blood pressure ( 27841878)
Interacting Genes		38 interacting genes: ASF1A ASF1B BPTF BRD7 CARM1 CHD1 CREBBP DCAF1 EP300 ESR1 HMGB2 HPF1 KAT2B KMT2A MAPK9 NEDD4 NOS3 PARP1 PARP10 PARP2 PELP1 PIM1 PPM1D PPP1CA PPP1CB SET SETD7 SMARCA1 SMARCA4 SMARCA5 SS18 SSRP1 SUPT16H SUV39H1 TLE2 UBN1 UHRF1 ZMYND11	2 interacting genes: BAZ1B H3-3A
Entrez ID		3020	6594
HPRD ID		03082	02055
Ensembl ID		ENSG00000163041	ENSG00000102038
Uniprot IDs		B2R4P9 P84243	A0A0A0MRP6 B7ZLQ5 P28370
PDB IDs		2L43 3ASK 3ASL 3AV2 3JVK 3MUK 3MUL 3QL9 3QLA 3QLC 3WTP 4GNE 4GNF 4GNG 4GU0 4GUR 4GUS 4GY5 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA 4L58 4N4I 4O62 4QQ4 4TMP 4U7T 4W5A 5B32 5B33 5BNV 5BNX 5DWQ 5DX0 5JA4 5JJY 5JLB 5KDM 5X7X 6A5L 6A5O 6A5P 6A5R 6A5T 6A5U 6HGT 6INQ 6IR9 6J4W 6J4X 6J4Y 6J4Z 6J50 6J51 6J9J 6PZV 6QXZ 6R0C 6RNY 6U04 7A08
Enriched GO Terms of Interacting Partners?
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