PRICKLE4 and CNTN4

		PRICKLE4	CNTN4
Description		prickle planar cell polarity protein 4	contactin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Adherens Junction Z Disc Filamentous Actin	Extracellular Region Plasma Membrane Axon Anchored Component Of Membrane
	Molecular Function	Molecular_function Actin Binding Zinc Ion Binding Muscle Alpha-actinin Binding	Cell-cell Adhesion Mediator Activity
	Biological Process	Heart Development Biological_process Actin Cytoskeleton Organization Muscle Structure Development	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Neuron Cell-cell Adhesion Nervous System Development Axonogenesis Axon Guidance Axonal Fasciculation Brain Development Neuron Projection Development Negative Regulation Of Neuron Differentiation Regulation Of Synaptic Plasticity Dendrite Self-avoidance
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Acenocoumarol maintenance dosage ( 19578179) Amyotrophic lateral sclerosis ( 19451621) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Atypical femoral fracture in phosphonate treatment ( 31006051) Autism spectrum disorder or schizophrenia ( 28540026) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood pressure ( 17903302) Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576 29875488) Body mass index (change over time) in chronic obstructive pulmonary disease ( 28044437) Brain connectivity ( 23471985) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime sleep phenotypes ( 27126917) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration ( 29346644) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels in HIV infection ( 33109212) High density lipoprotein cholesterol levels ( 31647587 34074324) High myopia ( 32428537) Intake of total sugars ( 31005972) Intelligence ( 22449649) Metabolite levels ( 23823483) Middle childhood and early adolescence aggressive behavior ( 26087016) Night sleep phenotypes ( 27126917) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to aripiprazole in schizophrenia ( 29503163) Restless legs syndrome ( 29029846) Schizophrenia ( 28991256 25056061 29483656 30285260 26198764) Sensorimotor dexterity ( 31596458) Serum immune biomarker levels ( 32066700) Serum uric acid levels ( 24379826) Thiopurine-induced pancreatitis in inflammatory bowel disease ( 29923122) Total ventricular volume ( 21116278) White blood cell count (basophil) ( 27863252)
Interacting Genes		10 interacting genes: AGXT CNTN4 GNE HOXA1 MTDH NEK6 OTX1 PLEKHN1 ZNF417 ZNF587	7 interacting genes: BARD1 BRCA1 CNTN6 ERAP2 GHRL PRICKLE4 TBCA
Entrez ID		29964	152330
HPRD ID		12884	16239
Ensembl ID		ENSG00000278224	ENSG00000144619
Uniprot IDs		Q2TBC4	Q8IWV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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