GPSM2 and INSC

Number of citations of the paper that reports this interaction (PubMedID 16458856)
9

Data Source:
HPRD (in vivo)

		GPSM2	INSC
Description		G protein signaling modulator 2	INSC spindle orientation adaptor protein
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cell Cortex Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region	Plasma Membrane Cell Cortex Protein-containing Complex Apical Cortex
	Molecular Function	Nucleotide Binding G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Dynein Complex Binding	Protein Binding Cytoskeletal Anchor Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Ran Protein Signal Transduction Regulation Of Catalytic Activity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly	Establishment Of Mitotic Spindle Orientation Nervous System Development Asymmetric Cell Division Regulation Of Asymmetric Cell Division Cell Differentiation Regulation Of Protein Stability Apical Protein Localization
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Expressive vocabulary in infants ( 25226531) Heel bone mineral density ( 30598549 28869591) Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: AGR2 ARHGEF40 CLCC1 DLG4 FXR1 FXR2 GAS2L1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC LRRC8E NUMA1 WHRN	17 interacting genes: CCDC187 GEM GPANK1 GPSM1 GPSM2 LHX3 LNX1 PARD3 PARD3B PRR35 RUSC1 SMARCD1 SORBS3 TEKT3 TTC23 USP54 ZNF587
Entrez ID		29899	387755
HPRD ID		06609	18803
Ensembl ID		ENSG00000121957	ENSG00000188487
Uniprot IDs		A0A024R0F8 B4DIF1 P81274	Q1MX18
PDB IDs		3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2	3SF4
Enriched GO Terms of Interacting Partners?
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