TRIB2 and PARVG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIB2	PARVG
Description		tribbles pseudokinase 2	parvin gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Kinase Inhibitor Activity Protein Binding Transcription Factor Binding Mitogen-activated Protein Kinase Kinase Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Regulator Activity	Actin Binding Protein Binding
	Biological Process	Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Interleukin-10 Production Regulation Of MAP Kinase Activity Negative Regulation Of Fat Cell Differentiation	Cell-matrix Adhesion Establishment Or Maintenance Of Cell Polarity Cell Projection Assembly Actin Cytoskeleton Reorganization Substrate Adhesion-dependent Cell Spreading
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) Cataracts ( 34127677) Chronotype ( 30696823) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Graves' disease ( 22922229) Heel bone mineral density ( 30598549) joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033) Methadone dose in opioid dependence ( 28115739) Multiple sclerosis ( 24076602) Optic cup area ( 25631615 28073927) Pericardial adipose tissue adjusted for height and weight ( 27918534) Pericardial fat ( 22589742 27918534) Platelet count ( 32888494)	Fasting glucose ( 33381925) Metabolite levels ( 23823483) Survival in colon cancer ( 25866641)
Interacting Genes		6 interacting genes: APP BTRC PARVG PRMT6 SLAMF7 UBQLN4	33 interacting genes: ALX4 ANTKMT APP CDHR3 CDSN CFAP53 CSF3 DDIT4L FOSL1 GADD45A HOMEZ ILK KCTD7 KLHL32 LHX3 LNX2 MEOX1 MEOX2 NBPF22P NBPF6 NDEL1 PDLIM7 POLR2G POU6F2 REL SERTAD2 TLE5 TRIB2 TRIM54 TSGA10IP USHBP1 ZNF426 ZNF677
Entrez ID		28951	64098
HPRD ID		18224	16285
Ensembl ID		ENSG00000071575	ENSG00000138964
Uniprot IDs		Q92519	A0A024R4U4 Q9HBI0
PDB IDs
Enriched GO Terms of Interacting Partners?
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