GRB7 and PHAX

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		GRB7	PHAX
Description		growth factor receptor bound protein 7	phosphorylated adaptor for RNA export
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Stress Granule Cell Projection	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Insulin Receptor Signaling Pathway Negative Regulation Of Translation Positive Regulation Of Cell Migration Stress Granule Assembly Negative Regulation Of Insulin Receptor Signaling Pathway	SnRNA Export From Nucleus Protein Transport RNA Stabilization
Pathways		GRB7 events in ERBB2 signaling Signaling by SCF-KIT Downstream signal transduction Tie2 Signaling RET signaling RND1 GTPase cycle	snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Asthma ( 31619474 28461288) Asthma or allergic disease (pleiotropy) ( 29785011) Asthma with severe exacerbations ( 32841424) Crohn's disease ( 28067908) Height ( 31562340) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Systemic lupus erythematosus ( 26502338) Type 1 diabetes (age at diagnosis) ( 33179336) Ulcerative colitis ( 28067908 20228799)	Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)
Interacting Genes		55 interacting genes: A1BG AGAP1 AR ATP5F1B CALM1 CAV1 CPNE6 CREBRF DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 ERBB4 FAM124B FCHO1 FGB FLAD1 GIGYF1 GIGYF2 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MET MSH2 PDGFRB PDHB PHAX PICK1 PKM PTK2 PTPRC RET RND1 RPS2 SETDB1 SHC1 STAC3 TCF12 TEK TGM5 TLE1 TMSB4X TRIM36 TRIM43 USP2 ZBTB16 ZNHIT1	19 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 ITIH1 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 STK3 TBCA TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		2886	51808
HPRD ID		03311	15122
Ensembl ID		ENSG00000141738	ENSG00000164902
Uniprot IDs		A0A0S2Z4F6 Q14451	Q9H814
PDB IDs		1MW4 1WGR 2L4K 2QMS 3PQZ 4WWQ 4X6S 5D0J 5EEL 5EEQ 5TYI 5U06 5U1Q	2XC7
Enriched GO Terms of Interacting Partners?
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