GRB7 and ATP5F1B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		GRB7	ATP5F1B
Description		growth factor receptor bound protein 7	ATP synthase F1 subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Focal Adhesion Cytoplasmic Stress Granule Cell Projection	Nucleus Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Mitochondrial Membrane Mitochondrial Nucleoid Proton-transporting ATP Synthase Complex Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding ATP Binding MHC Class I Protein Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Insulin Receptor Signaling Pathway Negative Regulation Of Translation Positive Regulation Of Cell Migration Stress Granule Assembly Negative Regulation Of Insulin Receptor Signaling Pathway	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy ATP Biosynthetic Process Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Intracellular PH Proton Transmembrane Transport
Pathways		GRB7 events in ERBB2 signaling Signaling by SCF-KIT Downstream signal transduction Tie2 Signaling RET signaling RND1 GTPase cycle	Mitochondrial protein import Mitochondrial protein import Formation of ATP by chemiosmotic coupling Transcriptional activation of mitochondrial biogenesis Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Phenethyl Isothiocyanate
Diseases
GWAS		Asthma ( 31619474 28461288) Asthma or allergic disease (pleiotropy) ( 29785011) Asthma with severe exacerbations ( 32841424) Crohn's disease ( 28067908) Height ( 31562340) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Systemic lupus erythematosus ( 26502338) Type 1 diabetes (age at diagnosis) ( 33179336) Ulcerative colitis ( 28067908 20228799)
Interacting Genes		55 interacting genes: A1BG AGAP1 AR ATP5F1B CALM1 CAV1 CPNE6 CREBRF DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 ERBB4 FAM124B FCHO1 FGB FLAD1 GIGYF1 GIGYF2 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MET MSH2 PDGFRB PDHB PHAX PICK1 PKM PTK2 PTPRC RET RND1 RPS2 SETDB1 SHC1 STAC3 TCF12 TEK TGM5 TLE1 TMSB4X TRIM36 TRIM43 USP2 ZBTB16 ZNHIT1	25 interacting genes: ANXA7 APOA1 ATP5F1C ATP5PF ATPAF1 ATPAF2 BYSL CDK4 CDKN1A FANCA GRB7 HMOX2 LNX2 OGT PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG
Entrez ID		2886	506
HPRD ID		03311	00044
Ensembl ID		ENSG00000141738	ENSG00000110955
Uniprot IDs		A0A0S2Z4F6 Q14451	P06576 V9HW31
PDB IDs		1MW4 1WGR 2L4K 2QMS 3PQZ 4WWQ 4X6S 5D0J 5EEL 5EEQ 5TYI 5U06 5U1Q
Enriched GO Terms of Interacting Partners?
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