SCAI and SOX7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCAI	SOX7
Description		suppressor of cancer cell invasion	SRY-box transcription factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Integral Component Of Membrane Nuclear Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of Transcription, DNA-templated	Endoderm Formation Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway
Pathways		RHO GTPases Activate Formins	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Smoking cessation ( 33082346) Worry too long after an embarrassing experience ( 29500382)	Alanine aminotransferase levels ( 33547301) Anxiety/tension (special factor of neuroticism) ( 30867560) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (beta diversity) ( 27723756) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Neutrophil percentage of white cells ( 32888494) Number of sexual partners ( 30643258) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 32154731) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494 27863252)
Interacting Genes		5 interacting genes: CDIPT ITPKB OGT PIN1 SOX7	8 interacting genes: APP DLC1 GLRX3 LZTS1 MTUS1 SCAI SMAD5 SMAD7
Entrez ID		286205	83595
HPRD ID		12941	18087
Ensembl ID		ENSG00000173611	ENSG00000171056
Uniprot IDs		Q8N9R8	Q9BT81
PDB IDs
Enriched GO Terms of Interacting Partners?
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