SCAI and ITPKB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCAI	ITPKB
Description		suppressor of cancer cell invasion	inositol-trisphosphate 3-kinase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Integral Component Of Membrane Nuclear Membrane	Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding	Inositol Hexakisphosphate Kinase Activity Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity
	Biological Process	Transcription, DNA-templated Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of Transcription, DNA-templated	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Phosphorylation Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Phosphatidylinositol Phosphate Biosynthetic Process Cellular Response To Calcium Ion
Pathways		RHO GTPases Activate Formins	Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Smoking cessation ( 33082346) Worry too long after an embarrassing experience ( 29500382)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Dentures ( 31235808) Eosinophil percentage of white cells ( 32888494) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 32201043 28892059 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		5 interacting genes: CDIPT ITPKB OGT PIN1 SOX7	13 interacting genes: CALM1 CEP70 CTDSP1 GOLGA2 IFT88 KRT34 PPP3CA PRKACA PRKCA PSME3 SCAI TRIM54 UBQLN2
Entrez ID		286205	3707
HPRD ID		12941	00942
Ensembl ID		ENSG00000173611	ENSG00000143772
Uniprot IDs		Q8N9R8	B2R9J0 P27987
PDB IDs
Enriched GO Terms of Interacting Partners?
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