CXCR3 and CXCL13

Number of citations of the paper that reports this interaction (PubMedID 11554781)
19

Data Source:
HPRD (in vivo, in vitro)

		CXCR3	CXCL13
Description		C-X-C motif chemokine receptor 3	C-X-C motif chemokine ligand 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding	Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding
	Biological Process	Angiogenesis Regulation Of Leukocyte Migration Apoptotic Process Chemotaxis Inflammatory Response Immune Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration T Cell Chemotaxis Calcium-mediated Signaling Regulation Of Cell Adhesion Cell Chemotaxis Chemokine-mediated Signaling Pathway	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Activation Of GTPase Activity Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Rheumatoid arthritis ( 32723749) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		9 interacting genes: C2CD2L CLDN19 CXCL10 CXCL11 CXCL13 CXCL9 FATE1 PF4 TMEM14A	11 interacting genes: ACKR4 CCL19 CCL21 CCL28 CCL4L1 CCR10 CXCR3 CXCR5 EEF1G FGF2 PF4V1
Entrez ID		2833	10563
HPRD ID		02936	05513
Ensembl ID		ENSG00000186810	ENSG00000156234
Uniprot IDs		P49682	O43927 Q53X90
PDB IDs			5CBA 5CBE 6VGJ 7JNY
Enriched GO Terms of Interacting Partners?
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